Clock catalogue

All 178, generated from the registry that scores them

This page is written from the registry the package ships, so it cannot describe a catalogue different from the one that scores. Every column below is a field the scoring code reads.

scale_type is the load-bearing one. It is not a label: it decides which downstream operations FALCONAge will perform, and asking for age acceleration on a pace_ratio clock is refused rather than computed.

178 clocks, registry schema 1.1.0.

What separates the three availability groups, and what a traced coefficient source means

Availability is about provenance, not about quality. A bundled clock has a coefficient file whose origin was followed back to the paper or its supplement and checksummed, so the same numbers come out on any machine with no network. An untraced clock has no public source for its coefficients, and a licensed one has a source whose terms do not permit redistribution. Copying a coefficient vector out of another package would move clocks into the bundled column and is the one route not taken here, because a number with no source behind it cannot be checked against anything.

Bundled: 69 clocks

Coefficients ship with the package, or the clock is a formula with none to ship. Works offline, no network, no licence.

Clock Year Predicts Scale Features Tissue Platform Paper
altumage 2022 chronological age age_years 20318 multi-tissue 27K, 450K de Lima Camillo 2022
bohlin 2016 gestational age gestational_weeks 96 cord blood 450K Bohlin 2016
cage 2023 chronological age age_years 3225 whole blood 450K, EPICv1 Bernabeu 2023
cellpopage 2024 cell-population passage age relative_score 42 cultured fibroblasts EPICv1 Lujan 2024
corticalclock 2020 chronological age age_years 347 brain cortex 450K Shireby 2020
deconvolutebloodepicbcell 2018 B cell proportion proportion 450 whole blood 450K, EPICv1 Salas 2018
deconvolutebloodepiccd4tcell 2018 CD4+ T cell proportion proportion 450 whole blood 450K, EPICv1 Salas 2018
deconvolutebloodepiccd8tcell 2018 CD8+ T cell proportion proportion 450 whole blood 450K, EPICv1 Salas 2018
deconvolutebloodepicmonocyte 2018 monocyte proportion proportion 450 whole blood 450K, EPICv1 Salas 2018
deconvolutebloodepicneutrophil 2018 neutrophil proportion proportion 450 whole blood 450K, EPICv1 Salas 2018
deconvolutebloodepicnkcell 2018 natural killer cell proportion proportion 450 whole blood 450K, EPICv1 Salas 2018
depressionbarbu 2021 major depressive disorder relative_score 196 whole blood EPICv1 Barbu 2021
dnamfili 2022 frailty risk relative_score 20 whole blood EPICv1, 450K Li 2022
dnamic 2025 intrinsic capacity relative_score 91 whole blood EPICv1 Fuentealba 2025
dnamphenoage 2018 phenotypic age age_years 513 whole blood 27K, 450K, EPICv1 Levine 2018
dnamstress 2023 stress exposure relative_score 211 whole blood EPICv1 Jung 2023
dnamtl 2019 leukocyte telomere length telomere_kb 140 whole blood 450K, EPICv1 Lu 2019
downsyndrome 2021 Down syndrome methylation score relative_score 652 neonatal blood spots EPICv1 Muskens 2021
dunedinpoam38 2020 pace of aging pace_ratio 46 whole blood 450K Belsky 2020
epicmithyper 2020 mitotic age divisions 184 B cells 450K, EPICv1 Duran-Ferrer 2020
epicmithypo 2020 mitotic age divisions 1164 B cells 450K, EPICv1 Duran-Ferrer 2020
epitoc1 2016 mitotic age divisions 385 multi-tissue, whole blood 450K Yang 2016
epitoc2 2020 mitotic age divisions 163 whole blood 450K Teschendorff 2020
epitoc3 2020 mitotic age divisions 170 cultured primary human cells, whole blood, multi-tissue, cord blood 450K, EPICv1 Teschendorff 2020
hannum 2013 chronological age age_years 71 whole blood 450K Hannum 2013
hd 2013 physiological dysregulation relative_score — blood clinical laboratory assays Cohen 2013
horvath2013 2013 chronological age age_years 353 multi-tissue 27K, 450K Horvath 2013
hrsinchphenoage 2022 phenotypic age age_years 959 whole blood 450K, EPICv1 Higgins-Chen 2022
hypoclock 2020 mitotic age divisions 678 multi-tissue 450K Teschendorff 2020
intrinclock 2024 chronological age age_years 370 multi-tissue 450K, EPICv1 Tomusiak 2024
kdm 2006 biological age age_years — blood clinical laboratory assays Klemera 2006
knight 2016 gestational age gestational_weeks 148 cord blood, neonatal blood spots 27K, 450K Knight 2016
leecontrol 2019 gestational age gestational_weeks 546 placenta 450K, EPICv1 Lee 2019
leerefinedrobust 2019 gestational age gestational_weeks 395 placenta 450K, EPICv1 Lee 2019
leerobust 2019 gestational age gestational_weeks 558 placenta 450K, EPICv1 Lee 2019
lin 2016 chronological age age_years 99 whole blood 27K, 450K Lin 2016
linage2 2025 mortality risk age_years 59 blood clinical laboratory assays Fong 2025
mayne 2017 gestational age gestational_weeks 62 placenta 27K, 450K Mayne 2017
mccartneyalcohol 2018 alcohol consumption gestational_weeks 450 whole blood EPICv1 McCartney 2018
mccartneybmi 2018 body mass index relative_score 1109 whole blood EPICv1 McCartney 2018
mccartneybodyfat 2018 body fat percentage relative_score 968 whole blood EPICv1 McCartney 2018
mccartneyeducation 2018 educational attainment relative_score 373 whole blood EPICv1 McCartney 2018
mccartneyhdlcholesterol 2018 HDL cholesterol relative_score 737 whole blood EPICv1 McCartney 2018
mccartneyldlcholesterol 2018 LDL cholesterol relative_score 233 whole blood EPICv1 McCartney 2018
mccartneysmoking 2018 smoking exposure relative_score 233 whole blood EPICv1 McCartney 2018
mccartneytotalcholesterol 2018 total cholesterol relative_score 204 whole blood EPICv1 McCartney 2018
mccartneytotalhdlratio 2018 total-to-HDL cholesterol ratio relative_score 412 whole blood EPICv1 McCartney 2018
mccartneywhr 2018 waist-to-hip ratio relative_score 226 whole blood EPICv1 McCartney 2018
meer 2018 chronological age age_years 435 multi-tissue RRBS Meer 2018
metaboage 2020 chronological age age_years 56 blood Nightingale Health 1H-NMR van den Akker 2020
metabohealth 2019 mortality mortality_log_hazard 14 blood Nightingale Health 1H-NMR Deelen 2019
pedbe 2020 chronological age age_years 94 buccal epithelium 450K, EPICv1 McEwen 2020
phenoage 2018 phenotypic age age_years 10 blood clinical laboratory assays Levine 2018
prostatecancerkirby 2017 prostate cancer relative_score 3 prostate 450K Kirby 2017
replitali 2022 replicative history divisions 87 cultured primary human cells EPICv1 Endicott 2022
skinandblood 2018 chronological age age_years 391 buccal epithelium, whole blood, epithelium, cultured fibroblasts, skin, cord blood 450K, EPICv1 Horvath 2018
stemtoc 2024 mitotic age divisions 371 multi-tissue, cultured human cells, whole blood 450K, EPICv1 Zhu 2024
stemtocvitro 2024 mitotic age divisions 629 multi-tissue, cultured human cells 450K, EPICv1 Zhu 2024
stoch 2024 chronological age age_years 353 sorted monocytes 450K Tong 2024
stocp 2024 chronological age age_years 513 sorted monocytes 450K Tong 2024
stocz 2024 chronological age age_years 514 sorted monocytes 450K Tong 2024
vidalbralo 2016 chronological age age_years 8 whole blood 27K Vidal-Bralo 2016
weidner 2014 chronological age age_years 3 whole blood 27K, bisulfite sequencing Weidner 2014
yingadaptage 2024 adaptive epigenetic age age_years_relative 999 whole blood 450K Ying 2024
yingcausage 2024 chronological age age_years 585 whole blood 450K Ying 2024
yingdamage 2024 damaging epigenetic age age_years_relative 1089 whole blood 450K Ying 2024
zhangblup 2019 chronological age age_years 319607 whole blood, saliva 450K, EPICv1 Zhang 2019
zhangen 2019 chronological age age_years 514 whole blood, saliva 450K, EPICv1 Zhang 2019
zhangmortality 2017 mortality risk mortality_log_hazard 10 whole blood 450K Zhang 2017

Untraced: 52 clocks

Catalogued, but no primary source for the coefficients has been established, so nothing is bundled. The metadata is real; the numbers are absent.

Clock Year Predicts Scale Features Tissue Platform Paper
abec 2020 chronological age age_years — whole blood EPICv1 Lee 2020
adbahadosingh 2021 late-onset Alzheimer’s disease relative_score — whole blood EPICv1 Bahado-Singh 2021
bocklandt 2011 EDARADD methylation relative_score — saliva 27K Bocklandt 2011
cabec 2020 chronological age age_years — whole blood 450K, EPICv1 Lee 2020
compil6 2021 interleukin-6 relative_score — whole blood 450K Stevenson 2021
ctsliver 2024 chronological age age_years — liver EPICv1 Tong 2024
cvdwesterman 2020 cardiovascular disease risk relative_score — whole blood 450K Westerman 2020
dnamfitage 2023 physical-fitness biological age age_years — whole blood 450K McGreevy 2023
dnamfitagegaitf 2023 gait speed relative_score — whole blood 450K McGreevy 2023
dnamfitagegaitm 2023 gait speed relative_score — whole blood 450K McGreevy 2023
dnamfitagegripf 2023 grip strength relative_score — whole blood 450K McGreevy 2023
dnamfitagegripm 2023 grip strength relative_score — whole blood 450K McGreevy 2023
dnamfitagevo2max 2023 VO2max relative_score — whole blood 450K McGreevy 2023
eabec 2020 chronological age age_years — whole blood EPICv1 Lee 2020
encen100 2023 chronological age age_years — whole blood, saliva, buccal epithelium 450K, EPICv1 Dec 2023
encen40 2023 chronological age age_years — whole blood, saliva, buccal epithelium 450K, EPICv1 Dec 2023
ensembleagehumanmouse 2025 relative age relative_score — multi-tissue, whole blood mammalian methylation array Haghani 2025
ensembleagestatic 2025 intervention-responsive epigenetic age age_years — multi-tissue Horvath MammalMethylChip40, Horvath MammalMethylChip320 Haghani 2025
ensembleagestatictop 2025 intervention-responsive epigenetic age age_years — multi-tissue Horvath MammalMethylChip40, Horvath MammalMethylChip320 Haghani 2025
epicga 2021 gestational age gestational_weeks — cord blood EPICv1 Haftorn 2021
fiage 2025 frailty index relative_score 53 whole blood EPICv1 no primary source traced, catalogued at
garagnani 2012 ELOVL2 methylation relative_score — whole blood 450K Garagnani 2012
gliasin 2024 chronological age age_years — brain cortex 450K Tong 2024
han 2020 chronological age age_years — whole blood 450K Han 2020
hep 2024 chronological age age_years — liver EPICv1 Tong 2024
hepatoxu 2017 hepatocellular carcinoma relative_score — plasma cell-free DNA targeted bisulfite sequencing Xu 2017
mammalian1 2023 chronological age age_years — multi-tissue Horvath MammalMethylChip40 Lu 2023
mammalian2 2023 chronological age age_years — multi-tissue Horvath MammalMethylChip40 Lu 2023
mammalian3 2023 chronological age age_years — multi-tissue Horvath MammalMethylChip40 Lu 2023
mammalianblood2 2023 chronological age age_years — blood Horvath MammalMethylChip40 Lu 2023
mammalianblood3 2023 chronological age age_years — blood Horvath MammalMethylChip40 Lu 2023
mammalianfemale 2023 sex relative_score — multi-tissue mammalian methylation array Li 2023
mammalianlifespan 2024 species maximum lifespan age_years — multi-tissue Horvath MammalMethylChip40 Li 2024
mammalianskin2 2023 chronological age age_years — skin Horvath MammalMethylChip40 Lu 2023
mammalianskin3 2023 chronological age age_years — skin Horvath MammalMethylChip40 Lu 2023
neusin 2024 chronological age age_years — brain cortex 450K Tong 2024
petkovich 2017 chronological age age_years — whole blood bisulfite sequencing Petkovich 2017
pipekelasticnet 2022 chronological age age_years — multi-tissue 27K, 450K, EPICv1 Pipek 2022
pipekfilteredh 2022 chronological age age_years — multi-tissue 27K, 450K, EPICv1 Pipek 2022
pipekretrainedh 2022 chronological age age_years — multi-tissue 27K, 450K, EPICv1 Pipek 2022
reedbmi 2020 BMI methylation score relative_score — whole blood, cord blood 450K Reed 2020
replitalinorm 2022 replicative history divisions — cultured fibroblasts EPICv1 Endicott 2022
retroelementagev1 2024 chronological age age_years — whole blood EPICv1 Ndhlovu 2024
retroelementagev2 2024 chronological age age_years — whole blood EPICv1 Ndhlovu 2024
senchronoage 2026 chronological age age_years — whole blood 450K, EPICv1 Kasamoto 2026
sencultureage 2026 cellular senescence relative_score — cultured fibroblasts, cultured mesenchymal stromal cells 450K, EPICv1 Kasamoto 2026
senmortalityage 2026 mortality risk mortality_log_hazard — whole blood 450K, EPICv1 Kasamoto 2026
stubbs 2017 chronological age age_years — multi-tissue, liver, lung, heart, brain cortex, skeletal muscle, cerebellum, spleen RRBS Stubbs 2017
thompson 2018 chronological age age_years — adipose tissue, blood, cerebellum, brain cortex, heart, kidney, liver, lung, skeletal muscle, spleen RRBS Thompson 2018
wu 2019 chronological age age_years — whole blood 27K, 450K Wu 2019
xchrom 2021 X-chromosome dosage relative_score — whole blood 450K, EPICv1 Wang 2021
ychrom 2021 Y-chromosome presence relative_score — whole blood 450K, EPICv1 Wang 2021

Licensed: 57 clocks

The architecture is implemented and tested; the coefficients are research-use-only and are not ours to distribute. Obtain a file and register it.

Clock Year Predicts Scale Features Tissue Platform Paper
cpgptgrimage3 2024 biological age age_years — whole blood 450K de Lima Camillo 2024
cpgptpcgrimage3 2024 biological age age_years — whole blood 450K de Lima Camillo 2024
dnamemrage 2026 electronic medical record age age_years — whole blood 450K, EPICv1 Chen 2026
dunedinpace 2022 pace of aging pace_ratio — whole blood EPICv1 Belsky 2022
grimage 2019 mortality risk age_years — whole blood 450K Lu 2019
grimage2 2022 mortality risk age_years — whole blood 450K Lu 2022
grimage2adm 2022 adrenomedullin relative_score — whole blood 450K Lu 2022
grimage2b2m 2022 beta-2-microglobulin relative_score — whole blood 450K Lu 2022
grimage2cystatinc 2022 cystatin C relative_score — whole blood 450K Lu 2022
grimage2gdf15 2022 GDF-15 relative_score — whole blood 450K Lu 2022
grimage2leptin 2022 leptin relative_score — whole blood 450K Lu 2022
grimage2loga1c 2022 hemoglobin A1c relative_score — whole blood 450K Lu 2022
grimage2logcrp 2022 C-reactive protein relative_score — whole blood 450K Lu 2022
grimage2packyrs 2022 smoking exposure relative_score — whole blood 450K Lu 2022
grimage2pai1 2022 PAI-1 relative_score — whole blood 450K Lu 2022
grimage2timp1 2022 TIMP-1 relative_score — whole blood 450K Lu 2022
omicmage 2026 biological age age_years — whole blood 450K, EPICv1 Chen 2026
pcdnamtl 2022 leukocyte telomere length telomere_kb — whole blood 450K Higgins-Chen 2022
pcgrimage 2022 mortality risk age_years — whole blood 450K Higgins-Chen 2022
pcgrimageadm 2022 adrenomedullin relative_score — whole blood 450K, EPICv1 Higgins-Chen 2022
pcgrimageb2m 2022 beta-2 microglobulin relative_score — whole blood 450K, EPICv1 Higgins-Chen 2022
pcgrimagecystatinc 2022 cystatin C relative_score — whole blood 450K, EPICv1 Higgins-Chen 2022
pcgrimagegdf15 2022 growth differentiation factor 15 relative_score — whole blood 450K, EPICv1 Higgins-Chen 2022
pcgrimageleptin 2022 leptin relative_score — whole blood 450K, EPICv1 Higgins-Chen 2022
pcgrimagepackyrs 2022 smoking pack-years relative_score — whole blood 450K, EPICv1 Higgins-Chen 2022
pcgrimagepai1 2022 plasminogen activator inhibitor 1 relative_score — whole blood 450K, EPICv1 Higgins-Chen 2022
pcgrimagetimp1 2022 TIMP metallopeptidase inhibitor 1 relative_score — whole blood 450K, EPICv1 Higgins-Chen 2022
pchannum 2022 chronological age age_years — whole blood 450K Higgins-Chen 2022
pchorvath2013 2022 chronological age age_years — multi-tissue 450K, EPICv1 Higgins-Chen 2022
pcphenoage 2022 phenotypic age age_years — whole blood 450K, EPICv1 Higgins-Chen 2022
pcskinandblood 2022 chronological age age_years — skin, whole blood, cultured fibroblasts 450K, EPICv1 Higgins-Chen 2022
retroclock 2025 retroelement methylation age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsage 2025 multisystem biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsageageprediction 2025 chronological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsageblood 2025 blood-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsagebrain 2025 brain-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsageheart 2025 cardiovascular-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsagehormone 2025 endocrine-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsageimmune 2025 immune-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsageinflammation 2025 inflammatory-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsagekidney 2025 renal-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsageliver 2025 hepatic-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsagelung 2025 pulmonary-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsagemetabolic 2025 metabolic-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
systemsagemusculoskeletal 2025 musculoskeletal-system biological age age_years — whole blood 450K, EPICv1 Sehgal 2025
twelvecelldeconvolutebloodepicbas 2022 basophil proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepicbmem 2022 memory B cell proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepicbnv 2022 naive B cell proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepiccd4mem 2022 memory CD4+ T cell proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepiccd4nv 2022 naive CD4+ T cell proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepiccd8mem 2022 memory CD8+ T cell proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepiccd8nv 2022 naive CD8+ T cell proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepiceos 2022 eosinophil proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepicmono 2022 monocyte proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepicneu 2022 neutrophil proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepicnk 2022 natural killer cell proportion proportion — purified blood leukocytes EPICv1 Salas 2022
twelvecelldeconvolutebloodepictreg 2022 regulatory T-cell proportion proportion — purified blood leukocytes EPICv1 Salas 2022

Querying it from code

reg = fa.registry.load()
reg.filter(availability="bundled", scale_type="age_years")
reg.search("mortality")
reg.compatible_with(data)
reg.get("horvath2013")
list_clocks(tier = "bundled")
list_clocks(search = "mortality")
compatible_clocks(d)
clock_info("horvath2013")