Derived abundance ratios (e.g. CD4:CD8), from the config's ratios: block

WHY CONFIG-DRIVEN, NOT HARDCODED: population names live in populations: (section 5.4) and are study-specific – a ratio hardcoded to "CD4 T cells"/"CD8 T cells" would silently mean nothing (or error) under a config using different labels. Each ratio supplies its own numerator/denominator population name, the same way each functional_blocks entry supplies its own marker list, so this stays generic across cohorts and panels.

Usage

compute_population_ratios(freq, ratios)

Arguments

freq

population_frequencies table (sample_id, population, pct_of_cd45_pos, is_control)

ratios

named list from cfg$ratios; each entry has numerator and denominator (population names from populations:) and an optional label

Value

data.frame(sample_id, ratio, population (=label), numerator, denominator, numerator_pct, denominator_pct, value, is_control), or NULL